Centres France    
  Prof. Maxime Dougados
Personal Maxime Dougados is Professor of Rheumatology at the René Descartes University-Paris 5 and Cochin Hospital in Paris, France. Within his research group, there are 6 fellows per year, who train in clinical epidemiology.
Interests The focus of Professor Dougados’ clinical practice is rheumatoid arthritis (RA), osteoarthritis (OA), spondylarthropathies and osteoporosis. He is particularly currently involved in 2 ongoing national cohorts of patients suffering from either early synovitis (ESPOIR cohort) or inflammatory back pain (DESIR cohort). His particular clinical interest is in clinical epidemiology. Research in his department focuses on outcome measures in musculoskeletal disorders.
Research
Projects

1. Clinical presentation of AS
2. Psychometric properties of Osteoarthritis Research Society International (OARSI) and Outcome Measures in Rheumatology (OMERACT) tools in OA
3. Predisposing factors of RA and AS
4. Ultrasonography scoring systems
Recent
Publications

Evaluation of several ultrasonography scoring systems of synovitis and comparison to clinical examination: Results from a prospective multi-center study of rheumatoid arthritis.
Dougados M, Jousse-Joulin S, Mistretta F, D'Agostino MA, Backhaus M, Bentin J, Chales G, Chary-Valckenaere I, Conaghan PG, Etchepare F, Gaudin P, Grassi W, van der Heijde D, Sellam J, Naredo E, Szkudlarek M, Wakefield R, Saraux A.
Ann Rheum Dis. 2009 Sep 9. [Epub ahead of print]PMID: 19740905 [PubMed - as supplied by publisher]

OARSI/OMERACT criteria of being considered a candidate for total joint replacement in knee/hip osteoarthritis as an endpoint in clinical trials evaluating potential disease modifying osteoarthritic drugs.
Dougados M, Hawker G, Lohmander S, Davis AM, Dieppe P, Maillefert JF, Gossec L.
J Rheumatol. 2009 Sep;36(9):2097-9.PMID: 19738220 [PubMed - indexed for MEDLINE]

Clinical and ultrasonographic predictors of joint replacement for knee osteoarthritis: results from a large, 3 year, prospective EULAR study.
Conaghan PG, D'Agostino MA, Le Bars M, Baron G, Schmidely N, Wakefield R, Ravaud P, Grassi W, Martin-Mola E, So A, Backhaus M, Malaise M, Emery P, Dougados M.
Ann Rheum Dis. 2009 May 10. [Epub ahead of print]PMID: 19433410 [PubMed - as supplied by publisher]

Evaluation of two strategies (initial methotrexate monotherapy vs its combination with adalimumab) in management of early active rheumatoid arthritis: data from the GUEPARD trial.
Soubrier M, Puéchal X, Sibilia J, Mariette X, Meyer O, Combe B, Flipo RM, Mulleman D, Berenbaum F, Zarnitsky C, Schaeverbeke T, Fardellone P, Dougados M.
Rheumatology (Oxford). 2009 Nov;48(11):1429-34. Epub 2009 Sep

Glucocorticoid sparing effect of tumour necrosis factor alpha inhibitors in rheumatoid arthritis in real life practice.
Seror R, Dougados M, Gossec L.
Clin Exp Rheumatol. 2009 Sep-Oct;27(5):807-13.

Hormonal replacement therapy may reduce the risk for RA in women with early arthritis who carry HLA-DRB1 *01 and/or *04 alleles by protecting against the production of anti-CCP: Results from the ESPOIR cohort.
Salliot C, Bombardier C, Saraux A, Combe B, Dougados M.
Ann Rheum Dis. 2009 Sep 9. [Epub ahead of print]

OARSI-OMERACT definition of relevant radiological progression in hip/knee osteoarthritis.
Ornetti P, Brandt K, Hellio-Le Graverand MP, Hochberg M, Hunter DJ, Kloppenburg M, Lane N, Maillefert JF, Mazzuca SA, Spector T, Utard-Wlerick G, Vignon E, Dougados M.
Osteoarthritis Cartilage. 2009 Jul;17(7):856-63. Epub 2009 Feb 9. Review.

Evaluation of different methods used to assess disease activity in rheumatoid arthritis: analyses of abatacept clinical trial data.
Dougados M, Schmidely N, Le Bars M, Lafosse C, Schiff M, Smolen JS, Aletaha D, van Riel P, Wells G.
Ann Rheum Dis. 2009 Apr;68(4):484-9. Epub 2008 Dec 11.PMID: 19074177 [PubMed - indexed for MEDLINE]

Elaboration of the preliminary Rheumatoid Arthritis Impact of Disease (RAID) score: a EULAR initiative.
Gossec L, Dougados M, Rincheval N, Balanescu A, Boumpas DT, Canadelo S, Carmona L, Daurès JP, de Wit M, Dijkmans BA, Englbrecht M, Gunendi Z, Heiberg T, Kirwan JR, Mola EM, Matucci-Cerinic M, Otsa K, Schett G, Sokka T, Wells GA, Aanerud GJ, Celano A, Dudkin A, Hernandez C, Koutsogianni K, Akca FN, Petre AM, Richards P, Scholte-Voshaar M, Von Krause G, Kvien TK.
Ann Rheum Dis. 2009 Nov;68(11):1680-5. Epub 2008 Dec 3.PMID: 19054825 [PubMed - indexed for MEDLINE]

Efficacy and safety of steroid injections for shoulder and elbow tendonitis: a meta-analysis of randomised controlled trials.
Gaujoux-Viala C, Dougados M, Gossec L.
Ann Rheum Dis. 2009 Dec;68(12):1843-9. Epub 2008 Dec 3.PMID: 19054817 [PubMed - in process]

   
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