|
 |
Centres France |
| Prof. Francis Berenbaum | |
| Personal | Francis Berenbaum is Head of the Department of Rheumatology at Pierre & Marie Curie University, APHP Hôpital Saint-Antoine in Paris, France. Within his research group, there are 4 scientific fellows per year, with numerous fellows within the clinical department. |
| Interests | The focus of Professor Berenbaum’s clinical practice is a multidisciplinary approach to hand osteoarthritis (OA). His focus in basic and translational research has been to investigate the role of mechanical stress, cytokines and growth factors on the release of pro-inflammatory and pro-degradative mediators in chondrocytes and cartilage explants. He his investigating the communication bone-cartilage in OA. |
| Research Projects |
1. Clinical research on hand OA 2. Mechanical stress and bone-cartilage biology 3. Inflammatory mediators and cartilage biology |
| Recent Publications |
De Ceuninck F, Berenbaum F. Proteomics: addressing the challenges of osteoarthritis. Drug Discov Today. 2009 Jul;14(13-14):661-7. Maheu E, Berenbaum F.Time for new outcome measures in hand osteoarthritis ? Nat Clin Pract Rheumatol. 2009 Mar;5(3):136-8. Blaise R, Mahjoub M, Salvat C, Barbe U, Brou C, Corvol MT, Savouret JF, Rannou F, Berenbaum F, Bausero P. Involvement of the Notch pathway in the regulation of matrix metalloproteinase 13 and the dedifferentiation of articular chondrocytes in murine cartilage. Arthritis Rheum. 2009 Feb;60(2):428-39. Sanchez C, Gabay O, Salvat C, Henrotin YE, Berenbaum F. Mechanical loading highly increases IL-6 production and decreases OPG expression by osteoblasts. Osteoarthritis Cartilage. 2009 Apr;17(4):473-81. |
| close window | print page |