Publications
in the last
two years |
1: Lago F, Gómez R, Gómez-Reino JJ, Dieguez C, Gualillo O. Adipokines as novel
modulators of lipid metabolism. Trends Biochem Sci. 2009 Oct;34(10):500-10. Epub
2009 Sep 2. Review. PubMed PMID: 19729309.
2: Suarez-Gestal M, Calaza M, Dieguez-Gonzalez R, Perez-Pampin E, Pablos JL,
Navarro F, Narvaez J, Marenco JL, Herrero-Beaumont G, Fernandez-Gutierrez B,
Lamas JR, de la Serna AR, Ortiz AM, Carreño L, Cañete JD, Caliz R, Blanco FJ,
Balsa A, Gomez-Reino JJ, Gonzalez A. Rheumatoid arthritis does not share most of
the newly identified systemic lupus erythematosus genetic factors. Arthritis
Rheum. 2009 Sep;60(9):2558-64. PubMed PMID: 19714582.
3: Navarro-Sarabia F, Ruiz-Montesinos D, Hernandez B, Navarro-Compán V, Marsal S,
Barcelo M, Perez-Pampín E, Gómez-Reino JJ. DAS-28-based EULAR response and HAQ
improvement in rheumatoid arthritis patients switching between TNF antagonists.
BMC Musculoskelet Disord. 2009 Jul 23;10:91. PubMed PMID: 19627609; PubMed
Central PMCID: PMC2724400.
4: Dieguez-Gonzalez R, Akar S, Calaza M, Gonzalez-Alvaro I, Fernandez-Gutierrez
B, Lamas JR, de la Serna AR, Caliz R, Blanco FJ, Pascual-Salcedo D, Velloso ML,
Perez-Pampin E, Pablos JL, Navarro F, Narvaez J, Lopez-Longo FJ, Herrero-Beaumont
G, Gomez-Reino JJ, Gonzalez A. Lack of association with rheumatoid arthritis of
selected polymorphisms in 4 candidate genes: CFH, CD209, eotaxin-3, and MHC2TA. J
Rheumatol. 2009 Aug;36(8):1590-5. Epub 2009 Jun 30. PubMed PMID: 19567623.
5: Evangelou E, Chapman K, Meulenbelt I, Karassa FB, Loughlin J, Carr A, Doherty
M, Doherty S, Gómez-Reino JJ, Gonzalez A, Halldorsson BV, Hauksson VB, Hofman A,
Hart DJ, Ikegawa S, Ingvarsson T, Jiang Q, Jonsdottir I, Jonsson H, Kerkhof HJ,
Kloppenburg M, Lane NE, Li J, Lories RJ, van Meurs JB, Näkki A, Nevitt MC,
Rodriguez-Lopez J, Shi D, Slagboom PE, Stefansson K, Tsezou A, Wallis GA, Watson
CM, Spector TD, Uitterlinden AG, Valdes AM, Ioannidis JP. Large-scale analysis of
association between GDF5 and FRZB variants and osteoarthritis of the hip, knee,
and hand. Arthritis Rheum. 2009 Jun;60(6):1710-21. PubMed PMID: 19479880.
6: Gómez R, Lago F, Gómez-Reino JJ, Dieguez C, Gualillo O. Expression and
modulation of ghrelin O-acyltransferase in cultured chondrocytes. Arthritis
Rheum. 2009 Jun;60(6):1704-9. PubMed PMID: 19479831.
7: Suarez-Gestal M, Calaza M, Endreffy E, Pullmann R, Ordi-Ros J, Domenico
Sebastiani G, Ruzickova S, Jose Santos M, Papasteriades C, Marchini M, Skopouli
FN, Suarez A, Blanco FJ, D'Alfonso S, Bijl M, Carreira P, Witte T, Migliaresi S,
Gomez-Reino JJ, Gonzalez A; European Consortium of SLE DNA Collections.
Replication of recently identified systemic lupus erythematosus genetic
associations: a case-control study. Arthritis Res Ther. 2009;11(3):R69. Epub 2009
May 14. PubMed PMID: 19442287; PubMed Central PMCID: PMC2714115.
8: Gómez R, Lago F, Gómez-Reino JJ, Gualillo O. Novel factors as therapeutic
targets to treat diabetes. Focus on leptin and ghrelin. Expert Opin Ther Targets.
2009 May;13(5):583-91. Review. PubMed PMID: 19397477.
9: Dieguez-Gonzalez R, Calaza M, Perez-Pampin E, Balsa A, Blanco FJ, Cañete JD,
Caliz R, Carreño L, de la Serna AR, Fernandez-Gutierrez B, Ortiz AM,
Herrero-Beaumont G, Pablos JL, Narvaez J, Navarro F, Marenco JL, Gomez-Reino JJ,
Gonzalez A. Analysis of TNFAIP3, a feedback inhibitor of nuclear factor-kappaB
and the neighbor intergenic 6q23 region in rheumatoid arthritis susceptibility.
Arthritis Res Ther. 2009;11(2):R42. Epub 2009 Mar 17. PubMed PMID: 19292917;
PubMed Central PMCID: PMC2688189.
10: Gomez R, Lago F, Gomez-Reino J, Dieguez C, Gualillo O. Adipokines in the
skeleton: influence on cartilage function and joint degenerative diseases. J Mol
Endocrinol. 2009 Jul;43(1):11-8. Epub 2009 Feb 24. Review. PubMed PMID: 19240195.
11: García S, Mera A, Gómez-Reino JJ, Conde C. Poly(ADP-ribose) polymerase
suppression protects rheumatoid synovial fibroblasts from Fas-induced apoptosis.
Rheumatology (Oxford). 2009 May;48(5):483-9. Epub 2009 Feb 19. PubMed PMID:
19228791.
12: Rego I, Fernández-Moreno M, Fernández-López C, Gómez-Reino JJ, González A,
Arenas J, Blanco FJ. Role of European mitochondrial DNA haplogroups in the
prevalence of hip osteoarthritis in Galicia, Northern Spain. Ann Rheum Dis. 2010
Jan;69(1):210-3. Epub . PubMed PMID: 19224903.
13: Meulenbelt I, Chapman K, Dieguez-Gonzalez R, Shi D, Tsezou A, Dai J, Malizos
KN, Kloppenburg M, Carr A, Nakajima M, van der Breggen R, Lakenberg N,
Gomez-Reino JJ, Jiang Q, Ikegawa S, Gonzalez A, Loughlin J, Slagboom EP. Large
replication study and meta-analyses of DVWA as an osteoarthritis susceptibility
locus in European and Asian populations. Hum Mol Genet. 2009 Apr
15;18(8):1518-23. Epub 2009 Jan 30. PubMed PMID: 19181678.
14: Westhovens R, Robles M, Ximenes AC, Nayiager S, Wollenhaupt J, Durez P,
Gomez-Reino J, Grassi W, Haraoui B, Shergy W, Park SH, Genant H, Peterfy C,
Becker JC, Covucci A, Helfrick R, Bathon J. Clinical efficacy and safety of
abatacept in methotrexate-naive patients with early rheumatoid arthritis and poor
prognostic factors. Ann Rheum Dis. 2009 Dec;68(12):1870-7. Epub 2009 Jan 5.
PubMed PMID: 19124524; PubMed Central PMCID: PMC2770104.
15: Pombo-Suarez M, Calaza M, Gomez-Reino JJ, Gonzalez A. Practical normalization
of mRNA expression in quantitative PCR for cartilage research. Osteoarthritis
Cartilage. 2009 Jun;17(6):818-9. Epub 2008 Nov 11. PubMed PMID: 19056303.
16: Rodriguez-Lopez J, Pombo-Suarez M, Loughlin J, Tsezou A, Blanco FJ,
Meulenbelt I, Slagboom PE, Valdes AM, Spector TD, Gomez-Reino JJ, Gonzalez A.
Association of a nsSNP in ADAMTS14 to some osteoarthritis phenotypes.
Osteoarthritis Cartilage. 2009 Mar;17(3):321-7. Epub 2008 Sep 14. PubMed PMID:
18790654.
17: Dieguez-Gonzalez R, Calaza M, Shi D, Meulenbelt I, Loughlin J, Tsezou A, Dai
J, Malizos KN, Slagboom EP, Kloppenburg M, Chapman K, Jiang Q, Kremer D,
Gomez-Reino JJ, Nakajima N, Ikegawa S, Gonzalez A. Testing the druggable
endothelial differentiation gene 2 knee osteoarthritis genetic factor for
replication in a wide range of sample collections. Ann Rheum Dis. 2009
Jun;68(6):1017-21. Epub 2008 Jul 14. PubMed PMID: 18625619.
18: Johnsen AK, Plenge RM, Butty V, Campbell C, Dieguez-Gonzalez R, Gomez-Reino
JJ, Shadick N, Weinblatt M, Gonzalez A, Gregersen PK, Benoist C, Mathis D. A
broad analysis of IL1 polymorphism and rheumatoid arthritis. Arthritis Rheum.
2008 Jul;58(7):1947-57. PubMed PMID: 18576312; PubMed Central PMCID: PMC2533126.
19: Pombo-Suarez M, Castaño-Oreja MT, Calaza M, Gomez-Reino J, Gonzalez A.
Differential upregulation of the three transforming growth factor beta isoforms
in human osteoarthritic cartilage. Ann Rheum Dis. 2009 Apr;68(4):568-71. Epub
2008 May 8. PubMed PMID: 18467513.
20: Dieguez-Gonzalez R, Calaza M, Perez-Pampin E, de la Serna AR,
Fernandez-Gutierrez B, Castañeda S, Largo R, Joven B, Narvaez J, Navarro F,
Marenco JL, Vicario JL, Blanco FJ, Fernandez-Lopez JC, Caliz R, Collado-Escobar
MD, Carreño L, Lopez-Longo J, Cañete JD, Gomez-Reino JJ, Gonzalez A. Association
of interferon regulatory factor 5 haplotypes, similar to that found in systemic
lupus erythematosus, in a large subgroup of patients with rheumatoid arthritis.
Arthritis Rheum. 2008 May;58(5):1264-74. PubMed PMID: 18438842.
21: Dieguez-Gonzalez R, Akar S, Calaza M, Perez-Pampin E, Costas J, Torres M,
Vicario JL, Velloso ML, Navarro F, Narvaez J, Joven B, Herrero-Beaumont G,
Gonzalez-Alvaro I, Fernandez-Gutierrez B, de la Serna AR, Carreño L, Lopez-Longo
J, Caliz R, Collado-Escobar MD, Blanco FJ, Fernandez-Lopez C, Balsa A,
Pascual-Salcedo D, Gomez-Reino JJ, Gonzalez A. Genetic variation in the nuclear
factor kappaB pathway in relation to susceptibility to rheumatoid arthritis. Ann
Rheum Dis. 2009 Apr;68(4):579-83. Epub 2008 Apr 23. PubMed PMID: 18434448.
22: Suarez-Gestal M, Ferreiros-Vidal I, Ortiz JA, Gomez-Reino JJ, Gonzalez A.
Analysis of the functional relevance of a putative regulatory SNP of PDCD1,
PD1.3, associated with systemic lupus erythematosus. Genes Immun. 2008
Jun;9(4):309-15. Epub 2008 Apr 10. PubMed PMID: 18401354.
23: Lago R, Gómez R, Lago F, Gómez-Reino J, Gualillo O. Leptin beyond body weight
regulation--current concepts concerning its role in immune function and
inflammation. Cell Immunol. 2008 Mar-Apr;252(1-2):139-45. Epub 2008 Mar 4.
Review. PubMed PMID: 18289518.
24: Lago R, Gomez R, Otero M, Lago F, Gallego R, Dieguez C, Gomez-Reino JJ,
Gualillo O. A new player in cartilage homeostasis: adiponectin induces nitric
oxide synthase type II and pro-inflammatory cytokines in chondrocytes.
Osteoarthritis Cartilage. 2008 Sep;16(9):1101-9. Epub 2008 Feb 7. PubMed PMID:
18261936.
25: Rodriguez-Lopez J, Mustafa Z, Pombo-Suarez M, Malizos KN, Rego I, Blanco FJ,
Tsezou A, Loughlin J, Gomez-Reino JJ, Gonzalez A. Genetic variation including
nonsynonymous polymorphisms of a major aggrecanase, ADAMTS-5, in susceptibility
to osteoarthritis. Arthritis Rheum. 2008 Feb;58(2):435-41. PubMed PMID: 18240210.
26: Pombo-Suarez M, Calaza M, Gomez-Reino JJ, Gonzalez A. Reference genes for
normalization of gene expression studies in human osteoarthritic articular
cartilage. BMC Mol Biol. 2008 Jan 29;9:17. PubMed PMID: 18226276; PubMed Central
PMCID: PMC2248200.
27: Lago F, Dieguez C, Gómez-Reino J, Gualillo O. Adipokines as emerging
mediators of immune response and inflammation. Nat Clin Pract Rheumatol. 2007
Dec;3(12):716-24. Review. PubMed PMID: 18037931.
28: Otero M, Lago R, Gómez R, Lago F, Gomez-Reino JJ, Gualillo O.
Phosphatidylinositol 3-kinase, MEK-1 and p38 mediate leptin/interferon-gamma
synergistic NOS type II induction in chondrocytes. Life Sci. 2007 Oct
27;81(19-20):1452-60. Epub 2007 Sep 26. PubMed PMID: 17935739.
29: García S, Bodaño A, Pablos JL, Gómez-Reino JJ, Conde C. Poly(ADP-ribose)
polymerase inhibition reduces tumor necrosis factor-induced inflammatory response
in rheumatoid synovial fibroblasts. Ann Rheum Dis. 2008 May;67(5):631-7. Epub
2007 Sep 21. PubMed PMID: 17890271.
30: Lago R, Gomez R, Dieguez C, Gomez-Reino JJ, Lago F, Gualillo O. Unlike
ghrelin, obestatin does not exert any relevant activity in chondrocytes. Ann
Rheum Dis. 2007 Oct;66(10):1399-400. PubMed PMID: 17881664.
31: Southam L, Rodriguez-Lopez J, Wilkins JM, Pombo-Suarez M, Snelling S,
Gomez-Reino JJ, Chapman K, Gonzalez A, Loughlin J. An SNP in the 5'-UTR of GDF5
is associated with osteoarthritis susceptibility in Europeans and with in vivo
differences in allelic expression in articular cartilage. Hum Mol Genet. 2007 Sep 15;16(18):2226-32. Epub 2007 Jul 6. PubMed PMID: 17616513
|
